Week 2 : Molecular Basis for Environmentally-Related Diseases (Cancer)

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TABLE OF CONTENTS
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Learning Objectives: 0:00:43
Case Scenario: 0:01:34
Supplemental Reading: 0:02:48
Estimated new cancer cases: 0:03:33
Estimated new cancer deaths:  0:04:21
What causes cancer? 0:05:07
Estimated Percentage of Cancer Deaths: 0:06:11
Types of Environmental Carcinogens: 0:08:49
What causes cancer: Environmental agents: 0:10:03
Environmental Cancer: Smoking: 0:12:10
Latency Period: 0:14:13
Dietary Factors Aflatoxin (Chemical) and Safrole (Chemical): 0:16:27
Environmental Cancer: Dietary Factors: 0:18:19
Naturally Occurring Carcinogens: 0:20:35
Bacterial Toxins (Chemical) and Microcystins: 0:21:55
Environmental Cancer: Occupational Exposures: 0:23:45
Environmental Cancer: Healthcare Industry: Anesthetic Gases: 0:24:46
Environmental Cancer: Healthcare Industry: Sterilant Gases: 0:25:42
Environmental Cancer: Healthcare Industry: Common Solvents, Disinfectants and Antiseptics: 0:26:25
Environmental Cancer: Reproductive/Sexual Behavior: 0:26:56
Environmental Cancer: Reproductive/Sexual Behavior (con’t) 0:27:06
What causes cancer? Heredity: 0:28:08
A Historical Perspective: 0:29:18
Multistage Carcinogenesis: 0:32:45
Multistage Chemical Carcinogenesis:  3 Mechanistic Stages of Carcinogenesis: 0:37:08
Multistage Chemical Carcinogenesis: INITIATION: 0:37:46
Multistage Chemical Carcinogenesis: PROMOTION: 0:37:17
Multistage Chemical Carcinogenesis: PROGRESSION: 0:41:18
Types of Multistage Chemical Carcinogenesis: 0:45:43 
Multistage Carcinogenesis: 0:46:16
Multistage Carcinogenesis: Multistep Oral: 0:49:21
Multistage Carcinogenesis: Oral images: 0:50:17
Cancer Cells vs Normal Cells: 051:31
Direct-Acting Carcinogens: 0:53:11
Indirect-Acting Carcinogens: 0:54:45
Analogy: Cells and Cars: 0:55:53
Analogy: Cells and Cars: 0:56:56
Analogy: Cars and Cells: 0:58:32
Specific Effects of Mutations: 1:00:22
Genetic Mutations: AACR Cancer Progress Report 2014: 1:01:03
Mutagenesis: 1:03:11
DNA Repair Pathways: 1:04:49
Cell Cycle: 0:05:23
G1-S Phase Checkpoint: 1:07:02
P16 Mutations in Oral Cancer: 1:10:57
Functional Analysis of P16 Proteins: 1:11:53
Gap Junctional Intercellular Communication and Carcinogenesis: 1:14:24
Trends in Cancer incidence Rates – Males: 1:17:24
Trends in Cancer incidence Rates – Females: 1:18:58
Trends in Cancer Death Rates – Males: 1:20:43
Trends in Cancer Death Rates – Females: 1:21:56
Trends in Cancer Death Rates – Sex and Race: 1:22:34
Lifetime Probability – Males: 1:23:29
Lifetime Probability – Females: 1:24:12
Five-year Survival Rates: 1:24:40
Chemoprevention: 1:25:12

YouTube url:	https://www.youtube.com/watch?v=joDBDpjQwOs
Created:	24. 9. 2017 23:26:05

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Week 2 : Molecular Basis for Environmentally-Related Diseases (Cancer)